RheOx® System
RheOx is a minimally invasive bronchoscopic therapy designed to treat the underlying abnormal mucus-producing cells associated with chronic bronchitis symptoms. Using non-thermal Pulsed Electric Field (PEF) energy, RheOx reduces these abnormal cells while preserving airway structure, allowing healthier tissue to regenerate.
Disclaimer: The RheOx system is an investigational device in the United States. Limited by Federal law to investigational use.
The RheOx system for the treatment of the symptoms of chronic bronchitis consists of a proprietary electrosurgical generator and a single-use catheter. The minimally-invasive bronchoscopic therapy delivers short bursts of Pulsed Electric Field (PEF) energy to induce non-thermal ablation of the abnormal mucus-producing cells in the airways, leaving the extracellular matrix intact so that the epithelium may rapidly regenerate.
Disclaimer: The RheOx system is an investigational device in the United States. Limited by Federal law to investigational use.
Bronchial rheoplasty procedure using the RheOx System
Pre- and post-treatment bronchoscopic images from a study patient.
Note the thick mucus before treatment, with resolution after treatment.
Pre-treatment
1 month after treatment with the RheOx System
Disclaimer: The RheOx system is an investigational device in the United States. Limited by Federal law to investigational use.
Clinical Evidence
Initial studies with the RheOx system showed technical feasibility and clinically meaningful improvements in the patients’ quality of life, with a favorable safety profile.
Improved quality of life1
– 1 .9 point
Reduction in CAT score*
– 1 .6 point
Reduction in SGRQ score*
*12 month results
CAT = COPD Assessment Test
SGRQ = St. George’s Respiratory Questionnaire
1. Valipour A, Fernandez-Bussy S, Ing AJ, et al. Bronchial rheoplasty for treatment of chronic bronchitis. Twelve-month results from a multicenter clinical trial. Am J Respir Crit Care Med. 2020;202(5):681-689. doi:10.1164/rccm.201908-1546OC
Completed clinical trials
Chronic Bronchitis
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