Data

Galvanize has conducted years of intensive research to elucidate the impact of its pulsed electric field technology on core biological processes.

Ongoing research is focused on developing energy into therapies for airway disease and oncology.

Oncology

Publications

Jimenez M, Flandes J, van der Heijden E, Ng C, Iding J, Garcia-Hierro J, Recalde-Zamacona B, Verhoeven R, Lau R, Moreno-Gonzalez A, Hatton B, Seshaiah P, Plentl M, Krimsky W. Safety and Feasibility of Pulsed Electric Field Ablation for Early-Stage Non-Small Cell Lung Cancer Prior to Surgical Resection. Accepted manuscript.

Knight D, Hillard H, Handran C, Kuhlman P. Pulsed electric field (PEF) treatment of refractory vulvar melanoma concurrently treated with immune checkpoint blockade demonstrating an abscopal response: A case report. Gynecologic Oncology Reports (2025). doi :10.1016/j.gore.2024.101671.

Nafie E, Pastori C, Acharya R, Kaviani R, Hunter D, Shalaby W, Krimsky WS, Neal RE 2nd. Understanding the aliya pulsed electric field dose-response relationship: Implications for ablation size, thermal load, and immune response in an orthotopic murine breast cancer model. PLoS One. 2025 Feb 13;20(2):e0318440. doi: 10.1371/journal.pone.0318440

Arciga BM, Walters DM, Kimchi ET, Staveley-O’Carroll KF, Li G, Teixeiro E, Rachagani S, Kaifi JT. Pulsed electric field ablation as a candidate to enhance the anti-tumor immune response to immune checkpoint inhibitors. Cancer Lett. 2025 Jan 28;609:217361. doi: 10.1016/j.canlet.2024.217361. Epub 2024 Nov 26. PMID: 39608443; PMCID: PMC11625606.

Rouhezamin MR, Fintelmann FJ, Huang AJ, Arellano RS, Smolinski-Zhao S, Patel DM, Wehrenberg-Klee EP, Uppot RN. Limited Effectiveness in Early Human Clinical Expérience with Pulsed Electrical Field Ablation. Journal of Vascular and Interventional Radiology (2024). doi: https://doi.org/10.1016/j.jvir.2024.10.033.

Kim, Daniel H. et al. Technical Feasibility and Safety of Image-Guided Biphasic Monopolar Pulsed Electric Field Ablation of Metastatic and Primary Malignancies. Journal of Vascular and Interventional Radiology,2024, epub ahead of print. https:// doi.org/10.1016/j.jvir.2024.08.003.

Rosa Kaviani, Robert E. Neal, David W. Hunter, William S. Krimsky, Tissue Radiologic and Pathologic Response to Biphasic Pulsed Electric Field Technology in a Porcine Model, Journal of Vascular and Interventional Radiology, 2024,ISSN 1051-0443, https://doi.org/10.1016/j.jvir.2024.08.015.

Jimenez M, Fernandez JM, Krimsky WS. Pulsed Electric Field (PEF) treatment of progressive non-small cell lung cancer concurrently treated with immune checkpoint blockade: A case report. Respir Med Case Rep. 2024 Mar 29;49:102018. doi: 10.1016/j.rmcr.2024.102018. PMID: 38601720; PMCID: PMC11004978.

C. Pastori, E. Nafie, M. S Wagh, J. Mammarappallil, R. Neal. Pulsed Electric Field Ablation versus Radiofrequency Thermal Ablation in Murine Breast Cancer Models: Anticancer Immune Stimulation, Tumor Response, and Abscopal Effects. J Vasc Interv Radiol. 2023 Nov 30:S1051-0443(23)00857-6. doi: 10.1016/j.jvir.2023.11.021.

Pastori C, Nafie E, Wagh MS, Hunt SJ, Neal RE 2nd. Neoadjuvant chemo-immunotherapy is improved with a novel pulsed electric field technology in an immune-cold murine model. PLoS One. 2024 Mar 25;19(3):e0299499. doi: 10.1371/journal.pone.0299499

Pastori C, Nafie E, Wagh MS, Mammarappallil JG, Neal RE 2nd. Pulsed Electric Field Ablation versus Radiofrequency Thermal Ablation in Murine Breast Cancer Models: Anticancer Immune Stimulation, Tumor Response, and Abscopal Effects. J Vasc Interv Radiol. 2024 Mar;35(3):442-451.e7. doi: 10.1016/j.jvir.2023.11.021 – Awarded at SIR 2025 with the “Outstanding Laboratory Investigation Award” among papers published on JVIR in 2024.

Abstracts

Bronchial Rheoplasty

Publications

Abstracts